Hormone replacement therapy, or HRT, is a medical treatment that involves replacing the body with hormones that may no longer be produced naturally, such as estrogen or progesterone. During menopause, the body produces less estrogen and progesterone, which can lead to uncomfortable symptoms.  This therapy is a versatile treatment that not only targets menopause symptoms in women but also proves effective for treating various hormonal imbalances in both men and women.

#1. What is HRT for men?

HRT stands for “hormone replacement therapy.” This relatively modern science helps reduce testosterone levels in a man’s bloodstream. The main goal, however, is to maintain a healthy chemical balance. Therefore, hormone replacement therapy is used even by guys not wanting to transition their gender. 

#2. How long does it take to work?

Each man will react differently to their HRT treatment. So, talk to a doctor about what to expect. In the meantime, be ready for a three to six-month wait before you start seeing any changes. That’s because it takes a while for the hormones to affect your body chemistry.

Meanwhile, understand that most men don’t feel the benefits right away. Within about a week though, many can tell a slight difference in their body’s functionality. Some even experience mood changes immediately. Either way, it’s a gradual process that should be monitored closely by a doctor. 

#3. What are the side effects of HRT for men?

Rest assured, your physique is going to change during hormone replacement therapy for men. In fact, there will be more side effects than that. Here are some of the things you can expect:

  • Decreased erections
  • Lowered sex drive
  • Softer skin
  • Atrophy of testicles
  • Breast development
  • Body fat redistribution
  • Loss of muscle mass
  • Weight gain

You might even experience a slowing of male pattern baldness because of the effects of estrogen. Depending on the look you’re going for, that could be a good or a bad thing.

#4. Can it be reversed?

If you change your mind about HRT or gender reassignment, all hope is not lost. That’s because hormone replacement therapy is mostly reversible. Many of the side effects will also stop happening when you quit taking the drugsHowever, the amount of reversal you experience depends on how long you were in treatment. 

#5. Is HRT for men safe?

Male hormone replacement therapy is generally safe, especially when it’s administered and closely monitored by a doctor. Still, there are some risks involved. Mainly, HRT can increase a man’s chances of developing blood clots or having a stroke. So, get in top physical health before you begin treatment. 

Certain experts say that you can offset some of the risks by donating blood every now and then. Also, you may experience a few uncommon side effects depending on your blood type. So, don’t be too alarmed if you notice sudden breast tenderness, get extra acne on your face or start suffering from sleep apnea. It’s all normal but you can talk to a doctor anyway if you’re concerned.


If you’re considering HRT for men, make an appointment with a professional and do not start treatments at home.

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